Chamaemelum nobile (L.) All.

Last updated: 04 April 2016

Scientific Name

Chamaemelum nobile (L.) All. 


Anacyclus aureus L., Anacyclus nobilis L. ex B.D.Jacks., Anthemis aurea DC., Anthemis nobilis L., Anthemis santolinoides Munby, Chamaemelum nobile f. discoideum (Boiss. ex Willk) Benedí, Chamaemelum nobile var. discoideum (Boiss. ex Willk.) A.Fern. [Unresolved], Chamaemelum nobile var. discoideum (Boiss.) P.Silva, Chamaemelum nobile f. nobile, Chameamelum nobile var. nobile, Chameamelum romanum Garsault [Invalid], Chamomilla nobilis Godr., Ormenis nobilis (L.) J. Gay ex Coss. & Germ., Ormenis nobilis subsp. aurea (L.) Maire, Ormenis nobilis var. nobilis [1]

Vernacular Name

English Chamomile, common chamomile, English chamomile, garden chamomile, Roman chamomile, true chamomile [2]
India Ai, babuna, babunah, babunaj, camanti, cankacuttam, chamaindoo poo, cimai camandi, cimai camanti, cimai camantippu, cimaiccamanti, gul babuna, gule-babunah, kuranku, utacamanti [2]
Brazil Camomile nobre, camomile odorante, camomile verdadeira, macela dourada [2].

Geographical Distributions

Chameamelum nobile is a perennial plant that has been found in Western Europe as well as Northern Africa. [3]

Botanical Description

C. nobile is a low-growing plant with white flowers, similar to daisies. The oblong leaves have an apple scent, while the taste of this plant is bitter. [3]


It is widely cultivated in countries such as Belgium and France. [3]

Chemical Constituent

Methanol extract of C. nobile flower heads has been reported to contain flavanoid glycoside compounds which specifically known as chemaemeloside. [4] [5]

C. nobile flowerheads extract has been reported to contain thirty-six different compounds namely isoamyl acetate, 2-methylbutyl acetate, isobutyl isobutyrate, 2-methyl-2-butenyl acetate, α-pinene, isobutyl methacrylate, camphene, 2-methyl-2-propenyl methacrylate, 2-metyl-2-propenyl isobutyrate, isopropyl angelate, isobutyl 2-methybutyrate, isoamyl asobutyrate, 2-methylbutyl isobutyrate, isoamyl methacrylate, 2-methylbutyl methacrylate, isobutyl angelate, (E)-2-methyl-2butenyl isobutyrate, 2-methyl-2-propenyl angelate, (E)-2-methyl-2-butenyl methacrylate, butyl angelate, butyl tiglate, 2-methylbutyl-2-methylbutyrate, 3-methylpentyl isobutyrate, trans-pinocarveol, 3-methylamyl methacrylate, isoamyl angelate, 2-methylbutyl angelate, alkyl angelate (B), pinocarvone, borneol, alkyl angelate (C), (E)-2-methyl-2-butenyl angelate, myrtenal, 3-methylamyl valerate, 2-hydroxy-2-methyl-3-butenyl angelate, 3-methylamyl angelate, (Z)-3-hexenyl angelate, and myrtenyl acetate. [6][7]

Plant Part Used

Flowers [4][5][6][7]

Traditional Use

No documentation.

Preclinical Data


No documentation.


No documentation.

Clinical Data

Clinical findings

One study examined the aromatic effects of Roman chamomile essential oil on 80 participants, which were divided into four groups: Aroma and arousal expectancy, aroma and sedation expectancy, aroma and no expectancy and lastly, no aroma controls. Cognitive function was reduced the greatest in the aroma and sedation expectancy rather than aroma alone. However, calmness was also seen in those expecting arousal. [8]

The essential oils of lavender, myrrh, neroli, mandarin, orange, grapefruit, rose and Roman chamomile were applied either as a sitz bath or a soap to women who had an episiotomy. The women were assigned to the aroma-sitz bath, aroma-soap or the control group. The results showed that aromatherapy applications could be useful in perineal healing. [9]

Cancer patients receiving palliative care were assigned to a massage either using only a carrier oil or carrier oil with the addition of Roman chamomile. Both groups showed decreased levels of anxiety. However, the addition of Roman chamomile improved the quality of life and physical and physiological symptoms during the massage. [10]


No documentation.

Side effects

No documentation.

Pregnancy/Breast Feeding

No documentation.

Age limitation

No documentation.

Adverse reaction

No documentation.

Interaction & Depletion

No documentation.

Interaction with drug

No documentation.

Interaction with other Herbs

No documentation.


Contact dermatitis could potentially occur, which has occurred with other plants from the Asteraceae family. [11]

Case Report

No documentation.


No documentation.

Poisonous Management

No documentation.

Line drawing

No documentation.


  1. The Plant List. Chamaemelum nobile (L.) All. 2013 ver1.1 [updated 2012, cited 2016 April 04] Available from
  2. Quattrocchi U. CRC World Dictionary of Medicinal and Poisonous Plants: Common Names, Scientific Names, Eponyms, Synonyms and Etymolohy; Volume II C-D Boca Raton, Florida: CRC Press; 2012. p. 208-209
  3. Simon JE, Chadwick AF, Craker LE. The Scientific Literature on Selected Herbs, and Aromatic and Medicinal Plants of The temperate Zone. University of Michigan: Archon Books; 1984. p. 770
  4. Tschan GM, Konig GM, Wright AD, Sticher O. Chamaemeloside, A New Flavanoid Glycoside from Chamaemelum nobile. Phytochemistry. 1996;41(2):643-646
  5. König GM, Wright AD, Keller WJ, Judd RL, Bates S, Day C. Hypoglycaemic Activity of An HMG-Containing Flavanoid Glycoside, Chamaemeloside, from Chamaemelum nobile. Planta Med. 1998;64(1998):612-614
  6. Farkas P, Hollá M, Vaverková S, Stahlová B, Tekel J, Havránek E. Composition of The Essential Oil from The Flowerheads of Chamaemelum nobile (L.) All. (Asteraceae) Cultivated in Slovak Republic. J. Essent. Oil Res. 2003;15(2003):83-85
  7. Antonelli A, Fabbri C. Study on Roman Chamomile (Chamaemelum nobile L. All.) Oil. J. Essent. Oil Res. 1998;10(1998):571-574
  8. Moss M, Howarth R, Wilkinson L, Wesnes K. Expectancy and The Aroma of Roman Chamomile Influence Mood and Cognition In Healthy Volunteers. Int. J. Aromather. 2006;16(2):63-73
  9. Hur MH, Han SH. [Clinical Trial of Aromatherapy on Postpartum Mother’s Perineal Healing] Taehan kanho hakhoe chi. 2004;34(1):53-62
  10. Wilkinson S, Aldridge J, Salmon I, Wilson B. An Evaluation of Aromatherapy Massage in Palliative Care. Palliat Med. 1999;13(5):409-417
  11. Paulsen E. Contact Sensitization from Compositae-Containing Herbal Remedies and Cosmetics. Contact Derm. 2002;47(4):189-198