How 5-Hydroxytryptophan (5-HTP) interacts with Antidepressants

Interaction type: Interactions

Interaction rating: Potential/Theoritical

Studies report that 5-HTP may act in the body like some of these medications, which may alter the effects of these medications and possibly the dose needed for treatment. Use with caution. (1)

These drugs include fluoxetine, fluvoxamine, paroxetine, sertraline, amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, trimipramine, maprotiline, mirtazapine, trazodone, bupropion, venlafaxine, nefazodone, citalopram, protriptyline, phenelzine, tranylcypromine, isocarboxazid

References

  1. View Abstract: Kahn RS, et al. L-5-hydroxytryptophan in the Treatment of Anxiety Disorders. J Affect Disord. Mar1985;8(2):197-200.