Title | Outcome parameters | Types and total included study | Findings |
In vitro inhibitory activities of 8-Hydroxyquinoline derivatives on dengue and West Nile virus: A descriptive review. | The ability of 8-Hydroxyquinoline derivatives to inhibit West Nile Virus or Dengue virus replication strain | Total 8 papers were included which consists of 6 papers: In vitro studies on 8-Hydroxyquinoline research on dengue virus, West Nile virus, and few other pathogens. 2 review papers: potential antiviral drug target based on the molecular structure of flavivirus | Currently, there are limited references available in order to suggest or dispute the use of 8-Hydroxyquinoline as a potential anti-dengue agent. Thus, further investigations with a proper methodology and outcomes need to be conducted to yield results that can be translated into in vivo and clinical studies. |
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