Articles

Picroliv protects against alcohol-induced chronic hepatotoxicity in rats.

Author

Rastogi R, Saksena S, Garg NK, Kapoor NK

Date

6/1996

Journal

Planta Med

Abstract

Daily administration of ethyl alcohol (3.76 g/kg, p.o.) for 45 days resulted in significant changes in several biochemical parameters of the liver and serum of albino rats. After exposure to alcohol for 30 days when Picroliv (12 mg/kg, p.o.), an iridoid glycoside fraction of Picrorhiza kurroa, was administered for 15 days along with alcohol, the degree of change in most of the parameters was reduced.