Lysine is an amino acid that is concentrated in muscle tissue and is essential for normal growth and development, as well as energy production. It is also involved in the body’s absorption of calcium, making it crucial for the health of bones and teeth.

Because it is so important for development, children require three to four times more lysine than adults. Infants in the first three to six months require even more.

The best food sources of lysine are fish, chicken, beef, lamb, wheat germ, milk, cottage cheese, and brewer’s yeast.

Dosage Info

Dosage Range

500mg to 4 grams daily.

Most Common Dosage

500mg, 2 times a day.

Dosage Forms

Capsules, tablets, and powder.

Interactions and Depletions


Reported Uses

Studies suggest that lysine may have the ability to treat symptoms of angina when taken together with vitamin C. (1) Other research suggests that lysine may control genital herpes and cold sores by reducing the number of outbreaks, reducing symptoms and speeding healing time. (2)

As mentioned, lysine is important for absorption of calcium. This benefit may have implications for the treatment and prevention of osteoporosis. (3)

Toxicities & Precautions


[span class=alert]Be sure to tell your pharmacist, doctor, or other health care providers about any dietary supplements you are taking. There may be a potential for interactions or side effects.[/span]


This dietary supplement is considered safe when used in accordance with proper dosing guidelines.

Pregnancy / Breast Feeding

To date, the medical literature has not reported any adverse effects related to fetal development during pregnancy or to infants who are breast-fed. Yet little is known about the use of this dietary supplement while pregnant or breast-feeding. Therefore, it is recommended that you inform your healthcare practitioner of any dietary supplements you are using while pregnant or breast-feeding.

Age Limitations

To date, the medical literature has not reported any adverse effects specifically related to the use of this dietary supplement in children. Since young children may have undiagnosed allergies or medical conditions, this dietary supplement should not be used in children under 10 years of age unless recommended by a physician.


  1. Pauling L. Case Report: Lysine/Ascorbate-related Amelioration of Angina Pectoris. J Orthomolecular Med. 1991;6:144-46.
  2. View Abstract: Griffith RS, et al. Success of L-lysine Therapy in Frequently Recurrent Herpes Simplex Infection. Treatment and Prophylaxis. Dermatologica. 1987;175(4):183-90.
  3. View Abstract: Civitelli R, Villareal DT, Agnusdei D, et al. Dietary L-lysine and Calcium Metabolism in Humans. Nutrition. Nov1992;8(6):400-05.