Ashwagandha : interaction with Anti-anxiety medications

Interaction type:
Interactions

Interaction rating:
Potential/Theoritical
Ashwagandha may effect a chemical in the brain called GABA, which may alter the effects of these medications and possibly the dose needed for treatment. Use with caution. (1)
These drugs include alprazolam, diazepam, lorazepam, clorazepate dipotassium, chlordiazepoxide, oxazepam, buspirone, doxepin, hydroxyzine, meprobamate

References

  1. Sudhir S, et al. Pharmacological Studies on Leaves of Withania somnifera. Planta Med. Feb1986;1:61-63.